Detailed information of SOX2

Dataset summary

TF Name: SOX2 Species: Danio rerio
Cell-type/Tissue: embryos, late blastula Condition/Source:
JASPAR ID: MA0142.1 MA0143.4 Collections: Permissive Robust
References: GEO GSE39780 GSM978984 GTRD EXP040985 PUBMED 23950494

External links

Statistical details

Model Peak caller Model ID Enrichment Zone TFBSs Score threshold Centrality p-value (log10)
DAMO MACS MA0142.1 55 4655 77.5 -5.3323781242491
DAMO MACS MA0143.4 86 7356 89.5 -11.6783200841669

131 datasets found for the same TF (SOX2) in other cell-types/tissues

TF Name Cell-line Condition/Source Collections Species Identifiers JASPAR ID
SOX2 BJ (fibroblasts) induced Permissive Robust Homo sapiens GSE36570 MA0143.3
SOX2 ZHBTc4 (embryonic stem cells) control Permissive Robust Mus musculus GSE28453 ... MA0143.4
SOX2 ZHBTc4 (embryonic stem cells) Tet Permissive Robust Mus musculus GSE28453 ... MA0143.4
SOX2 ZHBTc4 (embryonic stem cells) Tet Permissive Robust Mus musculus GSE28453 ... MA0143.4
SOX2 ZHBTc4 (embryonic stem cells) Tet Permissive Robust Mus musculus GSE28453 ... MA0143.4
SOX2 ZHBTc4 (embryonic stem cells) Tet Permissive Robust Mus musculus GSE28453 ... MA0143.4
SOX2 2TS22C (embryonic stem cells) Tet Permissive Robust Mus musculus GSE28453 ... MA0143.4
SOX2 neuralized embryoid body all trans retinoic acid (RA) and SAG for 3 days before harvested Permissive Robust Mus musculus GSE42132 ... MA0143.4
SOX2 embryonic stem cells none Permissive Robust Mus musculus GSE59378 ... MA0143.4
SOX2 2TS22C (embryonic stem cells) O-GlcNAc-deficient SOX2, long fragments Permissive Robust Mus musculus GSE69592 ... MA0143.4
SOX2 2TS22C (embryonic stem cells) O-GlcNAc-deficient SOX2, short fragments Permissive Robust Mus musculus GSE69592 ... MA0143.4
SOX2 2TS22C (embryonic stem cells) long fragments Permissive Robust Mus musculus GSE69592 ... MA0143.4
SOX2 2TS22C (embryonic stem cells) short fragments Permissive Robust Mus musculus GSE69592 ... MA0143.4
SOX2 OKSM reprogrammed embryonic fibroblasts Chaf1a KO Permissive Robust Mus musculus GSE72744 ... MA0143.4
SOX2 stomach SOX2 KO Permissive Robust Mus musculus GSE83965 ... MA0143.4
SOX2 embryonic stem cells PARP-1 KO Permissive Robust Mus musculus GSE74112 ... MA0143.4
SOX2 epiblast stem cells feeder free Permissive Robust Mus musculus GSE74636 ... MA0143.4
SOX2 ZHBTc4 (embryonic stem cells) untreated control Permissive Robust Mus musculus GSE87820 ... MA0143.4
SOX2 ZHBTc4 (embryonic stem cells) doxycycline-treated Permissive Robust Mus musculus GSE87820 ... MA0143.4
SOX2 Brg1fl/fl (embryonic stem cells) untreated control Permissive Robust Mus musculus GSE87820 ... MA0143.4
SOX2 Brg1fl/fl (embryonic stem cells) tamoxifen-treated Permissive Robust Mus musculus GSE87820 ... MA0143.4
SOX2 E3.5 embryonic stem cells asynchronous cell cycle Permissive Robust Mus musculus GSE92846 ... MA0143.4
SOX2 KH2 (embryonic stem cells) Overexpress Sox2-V5 tagged Permissive Robust Mus musculus GSE43275 ... MA0143.4
SOX2 KH2 (embryonic stem cells) Overexpress Sox2KE-V5 tagged; Sox2KE variant Permissive Robust Mus musculus GSE43275 ... MA0143.4
SOX2 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2 and Klf4 addition for 5 days Passage: 8 Permissive Robust Homo sapiens GSE81899 ... MA0143.4
SOX2 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2-VP16 (strong activator) and Klf4 addition for 5 days Passage: 8 Permissive Robust Homo sapiens GSE81899 ... MA0143.4
SOX2 MRC-5 (fetal lung fibroblasts) Genotype: wildtype Passage: 8 Permissive Robust Homo sapiens GSE81899 ... MA0143.4
SOX2 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2, Klf4 and Myc addition for 5 days Passage: 8 Permissive Robust Homo sapiens GSE81899 ... MA0143.4
SOX2 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2-VP16 (strong activator), Klf4 and Myc addition for 5 days Passage: 8 Permissive Robust Homo sapiens GSE81899 ... MA0143.4
SOX2 iPS (derived pancreatic precursor cells) Treatment: iPS protocol 3s2 Passage: 20 Permissive Robust Homo sapiens GSE81899 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, day3 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, day6 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, cKIT+, day9 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, sKIT+, day 12 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: GFP1+, MEF derived induced pluripotent stem cells Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: Thy1+, day3 cells refractory to MEF reprogramming. Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: Thy1+, day6 cells refractory to MEF reprogramming. Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: Thy1+, day3 cells refractory to MEF reprogramming. Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, day3 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: Thy1+, day6 cells refractory to MEF reprogramming. Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, day6 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, cKIT+, day9 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: SSEA1+, sKIT+, day 12 MEF reprogramming intermediates Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 MEF-1 (mouse embryonic fibroblasts) Genotype: het-het-het Strain: rtTA3-OKSM-Oct4GFP Treatment: GFP1+, MEF derived induced pluripotent stem cells Permissive Robust Mus musculus GSE101905 ... MA0143.4
SOX2 lung epithelial cells Strain: C57BL/6 Age: 8 week Genotype: wildtype Permissive Robust Mus musculus GSE108952 ... MA0143.4
SOX2 lung epithelial cells Strain: C57BL/6 Age: 8 week Genotype: ectopic Sox2 expression and Nkx2-1 deletion Permissive Robust Mus musculus GSE108952 ... MA0143.4
SOX2 lung epithelial cells Strain: C57BL/6 Age: 8 week Genotype: ectopic Sox2 expression Permissive Robust Mus musculus GSE108952 ... MA0143.4
SOX2 ES-E14 (E14, embryonic stem cells) Uhrf1 KO Permissive Robust Mus musculus GSE113913 ... MA0143.4
SOX2 Cell line generated from Lenti-Sox2-Cre infected KrasLSL-G12D/+;Trp53fl/fl (KPS) tumors Tissue: KPS1 cell line generated from Lenti-Sox2-Cre infected KrasLSL-G12D/+;Trp53fl/fl (KPS) tumors Permissive Robust Mus musculus GSE118244 ... MA0143.4
SOX2 Cell line generated from Lenti-Sox2-Cre infected KrasLSL-G12D/+;Trp53fl/fl (KPS) tumors Tissue: KPS2 cell line generated from Lenti-Sox2-Cre infected KrasLSL-G12D/+;Trp53fl/fl (KPS) tumors Permissive Robust Mus musculus GSE118244 ... MA0143.4
SOX2 Lung squamous cell carcinoma from Lkb1fl/fl;Ptenfl/fl (LP) mouse model; infected with Ad5-CMV-Cre virus; harvested approximately 10 months post-infection. Tissue: Lung squamous cell carcinoma from Lkb1fl/fl;Ptenfl/fl (LP) mouse model Permissive Robust Mus musculus GSE118244 ... MA0143.4
SOX2 cortex Sex: male Age: 1-2 months Strain: C57BL/6 Treatment: transduced with SOX2 Permissive Robust Mus musculus GSE85213 ... MA0143.4
SOX2 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shCtrl Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0143.4
SOX2 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shCtrl Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0143.4
SOX2 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shUbc9 Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0143.4
SOX2 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shUbc9 Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: l Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: l Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: l Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: l Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: l Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: FA Cell cecle: l Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: M Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: FA Cellcycle: M Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 Tg2a Cell type: ebryonic stem cells Treatment: DSGFA Cellcycle: M Permissive Robust Mus musculus GSE122589 ... MA0143.4
SOX2 differentiated embryonic stem cells Strain: C57BL/6N; Permissive Robust Mus musculus GSE93524 ... MA0143.4
SOX2 squamous cell carcinoma Conditions: low calcium (50uM) conditions for 24 hrs; Strain: C57BL/6; Tissue: skin; Permissive Robust Mus musculus GSE104142 ... MA0143.4
SOX2 squamous cell carcinoma Conditions: low calcium (50uM) conditions for 24 hrs; Strain: C57BL/6; Tissue: skin; Permissive Robust Mus musculus GSE104142 ... MA0143.4
SOX2 E14TG2A (embryonic stem cells) Treatment: no Dox; Cell type: 44iN; Characteristic: lif +; Permissive Robust Mus musculus GSE118898 ... MA0143.4
SOX2 E14TG2A (embryonic stem cells) Treatment: 1 ug/mL of Doxycycline; Cell type: 44iN; Characteristic: lif +; Permissive Robust Mus musculus GSE118898 ... MA0143.4
SOX2 NIH 3T3 (embryonic fibroblasts) Genotype: Overexpression of SOX2; Treatment: treated overnight with 500 ng/ml of Doxycycline one day after seeding; Permissive Robust Mus musculus GSE119782 ... MA0143.4
SOX2 hippocamus-derived neural progenitor cells Strain: mixed C57BL/6 x DBA; Source: hippocamus; Permissive Robust Mus musculus GSE90559 ... MA0143.4
SOX2 hippocamus-derived neural progenitor cells Strain: mixed C57BL/6 x DBA; Source: hippocamus; Permissive Robust Mus musculus GSE90559 ... MA0143.4
SOX2 esc Permissive Robust Homo sapiens GSE18292 MA0143.3
SOX2 H9 Permissive Robust Homo sapiens GSE46837 MA0143.3
SOX2 kyse70 Permissive Robust Homo sapiens GSE46837 MA0143.3
SOX2 Permissive Robust Homo sapiens GSE46837 MA0143.3
SOX2 iPSC (induced pluripotent stem cells) Permissive Robust Homo sapiens GSE56567 MA0143.3
SOX2 Permissive Robust Homo sapiens GSE67282 MA0143.3
SOX2 esc Permissive Robust Homo sapiens GSE69479 MA0143.3
SOX2 Permissive Robust Homo sapiens GSE69479 MA0143.3
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE11724 ... MA0143.4
SOX2 LN229 (glioblastoma) Permissive Robust Homo sapiens GSE23795 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE11431 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE44286 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE35496 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE35496 ... MA0143.4
SOX2 neural progenitors Permissive Robust Mus musculus GSE35496 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE35496 ... MA0143.4
SOX2 neural progenitors Permissive Robust Mus musculus GSE35496 ... MA0143.4
SOX2 embryonic stem cell-derived neural progenitors Permissive Robust Mus musculus GSE35496 ... MA0143.4
SOX2 STHdhQ7 (striatal cells) Permissive Robust Mus musculus GSE43429 ... MA0143.4
SOX2 HUES64 (embryonic stem cells) Permissive Robust Homo sapiens GSE46130 ... MA0143.4
SOX2 ZHBTc4-TS (trophoblast stem cells) Permissive Robust Mus musculus GSE51511 ... MA0143.4
SOX2 EGFP-TS3.5 TS (trophoblast stem cells) Permissive Robust Mus musculus GSE51511 ... MA0143.4
SOX2 D3 (embryonic stem cells) Permissive Robust Mus musculus GSE54103 ... MA0143.4
SOX2 multipotent otic progenitors Permissive Robust Mus musculus GSE62513 ... MA0143.4
SOX2 neural stem cells Permissive Robust Mus musculus GSE69859 ... MA0143.4
SOX2 OKSM reprogrammed embryonic fibroblasts Permissive Robust Mus musculus GSE72744 ... MA0143.4
SOX2 embryonic fibroblasts Permissive Robust Mus musculus GSE72744 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE74599 ... MA0143.4
SOX2 stomach Permissive Robust Mus musculus GSE83965 ... MA0143.4
SOX2 HUES64 (embryonic stem cells) Permissive Robust Homo sapiens GSE61475 ... MA0143.4
SOX2 HUES64 (embryonic stem cells) Permissive Robust Homo sapiens GSE61475 ... MA0143.4
SOX2 HUES64 (embryonic stem cells) Permissive Robust Homo sapiens GSE61475 ... MA0143.4
SOX2 HUES64 (embryonic stem cells) Permissive Robust Homo sapiens GSE61475 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE74112 ... MA0143.4
SOX2 epiblast stem cells Permissive Robust Mus musculus GSE74636 ... MA0143.4
SOX2 WA09 (embryonic stem cells) Permissive Robust Homo sapiens GSE76082 ... MA0143.4
SOX2 H9-derived neuroectoderm cells Permissive Robust Homo sapiens GSE76082 ... MA0143.4
SOX2 ES-E14 (E14, embryonic stem cells) Permissive Robust Mus musculus GSE89599 ... MA0143.4
SOX2 ES-E14 (E14, embryonic stem cells) Permissive Robust Mus musculus GSE89599 ... MA0143.4
SOX2 ES-E14 (E14, embryonic stem cells) Permissive Robust Mus musculus GSE89599 ... MA0143.4
SOX2 ES-E14 (E14, embryonic stem cells) Permissive Robust Mus musculus GSE89599 ... MA0143.4
SOX2 embryonic fibroblasts expressing OSKM for 48h Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 embryonic stem cells Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 embryonic fibroblasts expressing Sox2 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 embryonic fibroblasts expressing Sox2 from inducible system for 48h Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 embryonic fibroblasts expressing Sox2,Klf4 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 embryonic fibroblasts expressing Oct4,Sox2 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 embryonic fibroblasts expressing Oct4,Sox2,Klf4 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 pre-induced pluripotent stem cells Permissive Robust Mus musculus GSE90893 ... MA0143.4
SOX2 E3.5 embryonic stem cells Permissive Robust Mus musculus GSE92846 ... MA0143.4
SOX2 embryonic stem cell-derived neural progenitors Permissive Robust Mus musculus GSE33059 ... MA0143.4
SOX2 ES-E14 (E14, embryonic stem cells) Permissive Robust Mus musculus GSE113913 ... MA0143.4
SOX2 shsox2 Permissive Robust Homo sapiens GSE49404 MA0143.3
SOX2 iPSC (induced pluripotent stem cells) inhi Permissive Robust Homo sapiens GSE67282 MA0143.3
SOX2 iPSC (induced pluripotent stem cells) kdp53 inhi Permissive Robust Homo sapiens GSE67282 MA0143.3
SOX2 Permissive Robust Homo sapiens GSE49404 MA0143.3