Detailed information of KLF4

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Dataset summary

TF Name: KLF4 Species: Homo sapiens
Cell-type/Tissue: MRC-5 (fetal lung fibroblasts) Condition/Source: Treatment: Oct4, Sox2, Klf4 and Myc addition for 5 days Passage: 8
JASPAR ID: MA0039.4 Collections: Permissive
References: GEO GSE81899 GSM2183785 GSM2183786 GTRD EXP048959 PUBMED 28813671

External links

Models for profile: MA0039.4

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Summary plots

Statistical details

Model Peak caller Model ID Enrichment Zone TFBSs Score threshold Centrality p-value (log10)
DAMO MACS MA0039.4 7.5 35 88.3 0.0

60 datasets found for the same TF (KLF4) in other cell-types/tissues

TF Name Cell-line Condition/Source Collections Species Identifiers JASPAR ID
KLF4 CGR8 (embryonic stem cells) KLF4 overexpression Permissive Robust Mus musculus GSE49848 ... MA0039.4
KLF4 mixture of cell types KLF4 KO Permissive Mus musculus GSE65812 ... MA0039.4
KLF4 ES-E14 (E14, embryonic stem cells) EGFP KD Permissive Mus musculus GSE68400 ... MA0039.4
KLF4 ES-E14 (E14, embryonic stem cells) MBD3 KO Permissive Mus musculus GSE68400 ... MA0039.4
KLF4 B-cells Cebpa18h Permissive Mus musculus GSE71215 ... MA0039.4
KLF4 B-cells Cebpa18h, OSKM1d Permissive Mus musculus GSE71215 ... MA0039.4
KLF4 B-cells Cebpa18h, OSKM2d Permissive Mus musculus GSE71215 ... MA0039.4
KLF4 E3.5 embryonic stem cells asynchronous cell cycle Permissive Robust Mus musculus GSE92846 ... MA0039.4
KLF4 E3.5 embryonic stem cells asynchronous cell cycle Permissive Robust Mus musculus GSE92846 ... MA0039.4
KLF4 E3.5 embryonic stem cells asynchronous cell cycle Permissive Robust Mus musculus GSE92846 ... MA0039.4
KLF4 U87 (glioblastoma) R458A mutation Permissive Homo sapiens GSE97632 ... MA0039.4
KLF4 WA09 (embryonic stem cells) Treatment: under normal conditions Permissive Robust Homo sapiens GSE105028 ... MA0039.4
KLF4 WA09 (embryonic stem cells) Treatment: under heat shock conditions Permissive Robust Homo sapiens GSE105028 ... MA0039.4
KLF4 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2 and Klf4 addition for 5 days Passage: 8 Permissive Homo sapiens GSE81899 ... MA0039.4
KLF4 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2-VP16 (strong activator) and Klf4 addition for 5 days Passage: 8 Permissive Homo sapiens GSE81899 ... MA0039.4
KLF4 MRC-5 (fetal lung fibroblasts) Treatment: Oct4, Sox2-VP16 (strong activator), Klf4 and Myc addition for 5 days Passage: 8 Permissive Homo sapiens GSE81899 ... MA0039.4
KLF4 iPS (derived pancreatic precursor cells) Treatment: iPS protocol 3s2 Passage: 20 Permissive Homo sapiens GSE81899 ... MA0039.4
KLF4 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shCtrl Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0039.4
KLF4 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shCtrl Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0039.4
KLF4 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shUbc9 Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0039.4
KLF4 embryonic fibroblasts Cell type: MEF expressing OKSM for 4 days Treatment: shRNA Genotype: shUbc9 Passage: 1 Source: mouse embryonic fibroblast cells E13.5 Permissive Robust Mus musculus GSE99009 ... MA0039.4
KLF4 Akt (5MOI, mouse prostate stem cell line) Passage: 11 Permissive Robust Mus musculus GSE114772 ... MA0039.4
KLF4 MCF7 (Invasive ductal breast carcinoma) Treatment: none; Permissive Homo sapiens GSE41561 ... MA0039.4
KLF4 squamous cell carcinoma Conditions: low calcium (50uM) conditions for 24 hrs; Strain: C57BL/6; Tissue: skin; Permissive Mus musculus GSE104142 ... MA0039.4
KLF4 squamous cell carcinoma Conditions: high calcium (1.5mM) conditions for 24 hrs; Strain: C57BL/6; Tissue: skin; Permissive Mus musculus GSE104142 ... MA0039.4
KLF4 squamous cell carcinoma Treatment: 15,000 cells were injected intradermally to form tumor allografts; Strain: C57BL/6; Tissue: skin; Permissive Mus musculus GSE104142 ... MA0039.4
KLF4 squamous cell carcinoma Treatment: 5,000 cells were injected intradermally to form tumor allografts; Strain: C57BL/6; Tissue: skin; Permissive Mus musculus GSE104142 ... MA0039.4
KLF4 E14TG2A (embryonic stem cells) Conditions: cultured in 2i medium for 3 days; Permissive Robust Mus musculus GSE92407 ... MA0039.4
KLF4 E14TG2A (embryonic stem cells) Conditions: cultured in serum medium; Permissive Robust Mus musculus GSE92407 ... MA0039.4
KLF4 BJ (fibroblasts) INDUCED Permissive Robust Homo sapiens GSE36570 MA0039.4
KLF4 keratinocytes diff Permissive Robust Homo sapiens GSE57702 MA0039.4
KLF4 MCF7 (Invasive ductal breast carcinoma) Permissive Robust Homo sapiens ENCSR265WJC MA0039.4
KLF4 embryonic stem cells Permissive Robust Mus musculus GSE11431 ... MA0039.4
KLF4 mammary epithelial cells Permissive Mus musculus GSE49445 ... MA0039.4
KLF4 J1 (embryonic stem cells) Permissive Mus musculus GSE49137 ... MA0039.4
KLF4 J1 (embryonic stem cells) Permissive Mus musculus GSE49137 ... MA0039.4
KLF4 CGR8 (embryonic stem cells) Permissive Robust Mus musculus GSE49848 ... MA0039.4
KLF4 3T3-L1 (embryonic fibroblasts) Permissive Robust Mus musculus GSE56872 ... MA0039.4
KLF4 mixture of cell types Permissive Mus musculus GSE65812 ... MA0039.4
KLF4 B-cells Permissive Mus musculus GSE71215 ... MA0039.4
KLF4 CD4+ CD8+ thymocytes Permissive Mus musculus GSE76473 ... MA0039.4
KLF4 embryonic fibroblasts Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing OSKM for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic stem cells Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing Klf4 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing Klf4 from inducible system for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing Oct4,Klf4 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing Sox2,Klf4 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing Oct4,Sox2 from pMX vector for 48h Permissive Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing Oct4,Sox2,Klf4 from pMX vector for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing OSKM and Flag-Fra1 for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 embryonic fibroblasts expressing OSKM and Esrrb for 48h Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 pre-induced pluripotent stem cells Permissive Robust Mus musculus GSE90893 ... MA0039.4
KLF4 E3.5 embryonic stem cells Permissive Robust Mus musculus GSE92846 ... MA0039.4
KLF4 embryonic stem and neural progenitor cells Permissive Mus musculus GSE92846 ... MA0039.4
KLF4 E3.5 embryonic stem cells Permissive Robust Mus musculus GSE92846 ... MA0039.4
KLF4 U87 (glioblastoma) Permissive Robust Homo sapiens GSE97632 ... MA0039.4
KLF4 MCF7 (Invasive ductal breast carcinoma) Permissive Robust Homo sapiens GSE41561 MA0039.4
KLF4 hiPSC Permissive Robust Homo sapiens GSE56567 MA0039.4
KLF4 Permissive Homo sapiens GSE64557 MA0039.4