| HSF1 | 
     HepG2 (hepatoblastoma)  | 
     low-glucose DMEM with 0.5% BSA supplemented with 1uM forskolin and 1mM pyruvate for 6h. (Snyder)  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              ENCSR000EET
              
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     K562 (myelogenous leukemia)  | 
     no treatment  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE43579
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     K562 (myelogenous leukemia)  | 
     30 min at 42C  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE43579
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     K562 (myelogenous leukemia)  | 
     30 min at 42C  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE43579
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     STHdhQ7 (striatal cells)  | 
     cells were heat-shocked at 42°C for six hours  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE38000
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     STHdhQ111 (striatal cells)  | 
     cells were heat-shocked at 42°C for six hours  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE38000
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     spermatocytes  | 
     heatshock_38C  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE56735
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     spermatocytes  | 
     heatshock_43C  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE56735
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     after 12 min heat shock  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     after 12 min heat shock  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     after 60 min heat shock  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     after 60 min heat shock  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     HSF1KO  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     HSF1KO  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     HSF1KO, after 12 min heat shock  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     HSF1KO, after 12 min heat shock  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     HSF1KO, after 60 min heat shock  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     HSF1KO, after 60 min heat shock  | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     S. cerevisiae cells  | 
     control  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE108736
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     S. cerevisiae cells  | 
     heat shock  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE108736
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     S. cerevisiae cells  | 
     HSF1 TAP-tagged yeast cells; none; temperature: 30 C  | 
    
      
      
      Permissive
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE51251
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     S. cerevisiae cells  | 
     HSF1 TAP-tagged yeast cells; none; temperature: 39 C  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE51251
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     SK1 meiotic cells (4 hours)  | 
     Treatment: non heat shock, 30 degrees; Genotype: Wildtype;   | 
    
      
      
      Permissive
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE117653
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     SK1 meiotic cells (4 hours)  | 
     Treatment: 5 min heat shock, 39 degree; Genotype: Wildtype;  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE117653
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     SK1 meiotic cells (4 hours)  | 
     Treatment: 120 min heat shock, 39 degree; Genotype: Wildtype;  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Saccharomyces cerevisiae | 
    
      
        
          
            
              
              GSE117653
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0319.1
        
      
     | 
  
  
    
    | HSF1 | 
     WA09 (embryonic stem cells)  | 
     Treatment: under normal conditions  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE105028
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     WA09 (embryonic stem cells)  | 
     Treatment: under heat shock conditions  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE105028
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     CUTLL1 (T-cell lymphoblastic lymphoma 1)  | 
     Treatment: no  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE90716
              
            
          
            
            ...
            
          
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     P12 (P12-Ichikawa, Childhood T acute lymphoblastic leukemia)  | 
     Treatment: no  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE90716
              
            
          
            
            ...
            
          
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     BPE (mammary epithelial cells)  | 
     HEAT  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     | 
     tumor  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     | 
     tumor  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     | 
     HEAT  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     MCF10A (breast epithelial cells)  | 
     HEAT  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     HCT-116 (colon carcinoma)  | 
     KOFBXW7  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE57398
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     GM12878 (female B-cells lymphoblastoid cell line)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              ENCSR009MBP
              
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     MCF7 (Invasive ductal breast carcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              ENCSR062HDL
              
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     mesenchymal stem cells-derived adipocytes  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE24326
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     STHdhQ7 (striatal cells)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE38000
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     STHdhQ111 (striatal cells)  | 
     | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE38000
              
            
          
            
            ...
            
          
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     spermatocytes  | 
     | 
    
      
      
      Permissive
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE56735
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     embryonic fibroblasts  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Mus musculus | 
    
      
        
          
            
              
              GSE71708
              
            
          
            
            ...
            
          
        
      
        
      
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     BPLER (mammary epithelial cells)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     BT-20 (breast invasive ductal carcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     HCT-15 (colon carcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     HMLER (mammary epithelial cells)  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     HT29 (colon adenocarcinoma)  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     MCF7 (Invasive ductal breast carcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     NCI-H1703 (squamous cell lung carcinoma )  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     NCI-H441 (squamous cell lung carcinoma )  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     NCI-H838 (lung adenocarcinoma)  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     SK-BR-3 (breast adenocarcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     SW620 (colon adenocarcinoma)  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     ZR-75-1 (invasive ductal carcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE38901
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     M0-91 (acute myeloid leukemia)  | 
     27A_100UM  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE45852
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     M0-91 (acute myeloid leukemia)  | 
     27A_20UM  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE45852
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     M0-91 (acute myeloid leukemia)  | 
     CHX_10UM  | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE45852
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     MCF7 (Invasive ductal breast carcinoma)  | 
     CHX_10UM  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE45852
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     U2OS (osteosarcoma)  | 
     HEAT  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE60984
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     U2OS (osteosarcoma)  | 
     HEAT_20  | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE60984
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     M0-91 (acute myeloid leukemia)  | 
     | 
    
      
      
      Permissive
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE45852
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     | 
  
  
    
    | HSF1 | 
     MCF7 (Invasive ductal breast carcinoma)  | 
     | 
    
      
      
      Permissive
      
      Robust
      
     | 
    Homo sapiens | 
    
      
        
          
            
              
              GSE45852
              
            
          
        
      
     | 
    
      
        
        MA0486.2
        
      
     |