Detailed information of RUNX1

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Dataset summary

TF Name: RUNX1 Species: Homo sapiens
Cell-type/Tissue: CUTLL1 (T-cell lymphoblastic lymphoma 1) Condition/Source: vehicle
JASPAR ID: MA0002.2 Collections: Permissive Robust
References: GEO GSE51800 GSM1252931 GTRD EXP032406 PUBMED 24374627

External links

Models for profile: MA0002.2

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Summary plots

Statistical details

Model Peak caller Model ID Enrichment Zone TFBSs Score threshold Centrality p-value (log10)
DAMO MACS MA0002.2 74 37352 83.2 -30.3670041762057

135 datasets found for the same TF (RUNX1) in other cell-types/tissues

TF Name Cell-line Condition/Source Collections Species Identifiers JASPAR ID
RUNX1 K562 (myelogenous leukemia) 24 hours following induction with TPA Permissive Robust Homo sapiens GSE24777 ... MA0002.2
RUNX1 differentiated embryonic stem cells Runx1+/VE-cadherin+/CD41+ Permissive Mus musculus GSE29514 ... MA0002.2
RUNX1 differentiated embryonic stem cells Runx1+/VE-cadherin-/CD41+ Permissive Robust Mus musculus GSE29514 ... MA0002.2
RUNX1 L8057 (megakaryoblastic leukemia) 50nM TPA Permissive Robust Mus musculus GSE33653 ... MA0002.2
RUNX1 dendritic cells LPS, 0 min Permissive Robust Mus musculus GSE36099 ... MA0002.2
RUNX1 dendritic cells LPS, 120 min Permissive Mus musculus GSE36099 ... MA0002.2
RUNX1 dendritic cells LPS, 60 min Permissive Mus musculus GSE36099 ... MA0002.2
RUNX1 hematopoietic cells dox Permissive Robust Mus musculus GSE40235 ... MA0002.2
RUNX1 embryonic stem cell-derived myeloid progenitors induced Permissive Robust Mus musculus GSE64589 ... MA0002.2
RUNX1 CD4+ T-cells PMA 120 min Permissive Mus musculus GSE67443 ... MA0002.2
RUNX1 embryonic stem cell-derived hematopoietic progenitors none Permissive Robust Mus musculus GSE69099 ... MA0002.2
RUNX1 embryonic stem cell-derived macrophages none Permissive Robust Mus musculus GSE69099 ... MA0002.2
RUNX1 FDC-P1 (lymphoblasts) RUNX-ERt2 Permissive Robust Mus musculus GSE81179 ... MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) MEIS2 KD Permissive Robust Homo sapiens GSE81321 ... MA0002.2
RUNX1 SKH1 (chronic myelogenous leukemia, BCR-ABL1 positive) RUNX1-EVI1 KD after 10 days Permissive Robust Homo sapiens GSE87283 ... MA0002.2
RUNX1 bone marrow Untreated Permissive Robust Mus musculus GSE87623 ... MA0002.2
RUNX1 bone marrow Vitamin C Permissive Robust Mus musculus GSE87623 ... MA0002.2
RUNX1 ME-1 (acute myeloid leukemia ) Treatment: DMSO for 6 hr; CellType: human inv(16) leukemia cell line; Permissive Robust Homo sapiens GSE101789 ... MA0002.2
RUNX1 ME-1 (acute myeloid leukemia ) Treatment: Al-10-49 (1uM) for 6 hr; CellType: human inv(16) leukemia cell line; Permissive Robust Homo sapiens GSE101789 ... MA0002.2
RUNX1 KP66(mouse sleen cells) Genotype: gfil1 KO; Permissive Robust Mus musculus GSE103255 ... MA0002.2
RUNX1 WT132(mouse spleen) Genotype: wildtype gfi1; Permissive Mus musculus GSE103255 ... MA0002.2
RUNX1 HEE (human epididymis epithelial cells) Treatment: without treatment of R1881 (methyltrienolone) Permissive Homo sapiens GSE109061 ... MA0002.2
RUNX1 HEE (human epididymis epithelial cells) Treatment: treatment of 1 nM R1881 (methyltrienolone) for 12 -16 hr Permissive Robust Homo sapiens GSE109061 ... MA0002.2
RUNX1 HEE (human epididymis epithelial cells) Treatment: without treatment of R1881 (methyltrienolone) Permissive Homo sapiens GSE109061 ... MA0002.2
RUNX1 HEE (human epididymis epithelial cells) Treatment: treatment of 1 nM R1881 (methyltrienolone) for 12 -16 hr Permissive Homo sapiens GSE109061 ... MA0002.2
RUNX1 NALM-6 (adult B acute lymphoblastic leukemia) Tissue: Peripheral blood Permissive Robust Homo sapiens GSE109377 ... MA0002.2
RUNX1 NALM-6 (adult B acute lymphoblastic leukemia) Tissue: Peripheral blood Permissive Robust Homo sapiens GSE109377 ... MA0002.2
RUNX1 pre-B-lymphoblast cells with BCP-ALL DIsease: human precursor leukemia (BCP-ALL) Tissue: bone marrow Permissive Robust Homo sapiens GSE109377 ... MA0002.2
RUNX1 pre-B-lymphoblast cells with BCP-ALL DIsease: human precursor leukemia (BCP-ALL) Tissue: bone marrow Permissive Robust Homo sapiens GSE109377 ... MA0002.2
RUNX1 pre-B-lymphoblast cells with BCP-ALL DIsease: human precursor leukemia (BCP-ALL) Tissue: bone marrow Permissive Robust Homo sapiens GSE109377 ... MA0002.2
RUNX1 pre- leukemia stem cells (CD34+ human cord blood cells) Treatment: untreated Permissive Homo sapiens GSE80773 ... MA0002.2
RUNX1 Lin- BM derived DN1 cells Genotype: Lin-, CD45+, Kit+,CD25- Strain: C57BL6/J Treatmen: Cultured on OP9DL1 Tissue: bone marrow Permissive Mus musculus GSE103953 ... MA0002.2
RUNX1 Lin- BM derived DN1 cells Genotype: Lin-, CD45+, Kit+,CD25- Strain: C57BL6/J Treatmen: Cultured on OP9DL1 Tissue: bone marrow Permissive Mus musculus GSE103953 ... MA0002.2
RUNX1 Lin- BM derived DN3 cells Strain: C57BL6/J Treatment: Cultured on OP9DL1 Genotype: Lin-CD45+Kit-CD25+ Permissive Robust Mus musculus GSE103953 ... MA0002.2
RUNX1 Lin- BM derived DN3 cells Strain: C57BL6/J Treatment: Cultured on OP9DL1 Genotype: Lin-CD45+Kit-CD25+ Permissive Robust Mus musculus GSE103953 ... MA0002.2
RUNX1 hemogenic endothelium Strain: 129P2/OlaHsd Treatment: untreated, no DOX, uniduced Permissive Mus musculus GSE104045 ... MA0002.2
RUNX1 hemogenic endothelium Strain: 129P2/OlaHsd Treatment: induced by treatment with DOX Permissive Robust Mus musculus GSE104045 ... MA0002.2
RUNX1 hemogenic endothelium Strain: 129P2/OlaHsd Treatment: JQ1, induced by treatment with DOX Permissive Robust Mus musculus GSE104045 ... MA0002.2
RUNX1 lin-bone marrow Strain: C57BL6/J Genotype: wildtype DN3 Treatment: cultured on OP9DL1 Permissive Robust Mus musculus GSE110305 ... MA0002.2
RUNX1 lin-bone marrow Strain: C57BL6/J Genotype: wildtype DN3 Treatment: cultured on OP9DL1 Permissive Robust Mus musculus GSE110305 ... MA0002.2
RUNX1 lin-bone marrow Strain: C57BL6/J Genotype: Bcl11b knockout DN3 Treatment: cultured on OP9DL1 Permissive Robust Mus musculus GSE110305 ... MA0002.2
RUNX1 lin-bone marrow Strain: C57BL6/J Genotype: Bcl11b knockout DN3 Treatment: cultured on OP9DL1 Permissive Robust Mus musculus GSE110305 ... MA0002.2
RUNX1 BMDM (bone marrow-derived macrophages) KLA 1h; C57BL/6J strain Permissive Robust Mus musculus GSE109965 ... MA0002.2
RUNX1 BMDM (bone marrow-derived macrophages) C57BL/6J strain Permissive Robust Mus musculus GSE109965 ... MA0002.2
RUNX1 EML -C1(EML, clone 1) Passage: 4-5 Strain: C57BL/6 Permissive Robust Mus musculus GSE75186 ... MA0002.2
RUNX1 pro-T-tumor derived (Scid.adh.2c2 cells) Treatment: Transduced with pMxs-Mock-hNGFR Strain: CB17-Prkdc<scid> mice Permissive Robust Mus musculus GSE93755 ... MA0002.2
RUNX1 pro-T-tumor derived (Scid.adh.2c2 cells) Treatment: Transduced with pMxs-Mock-hNGFR Strain: CB17-Prkdc<scid> mice Permissive Robust Mus musculus GSE93755 ... MA0002.2
RUNX1 pro-T-tumor derived (Scid.adh.2c2 cells) Treatment: Transduced with pMxs-PU.1-hNGFR Strain: CB17-Prkdc<scid> mice Permissive Robust Mus musculus GSE93755 ... MA0002.2
RUNX1 pro-T-tumor derived (Scid.adh.2c2 cells) Treatment: Transduced with pMxs-PU.1-hNGFR Strain: CB17-Prkdc<scid> mice Permissive Robust Mus musculus GSE93755 ... MA0002.2
RUNX1 Dombi23 (primary keratinocytes) day 0 of differentiation Permissive Homo sapiens GSE98483 ... MA0002.2
RUNX1 ILC2 (type 2 Innate lympoid cells) Growth: with IL-2/IL-7/IL-33 for 4 weeks, and with IL-33 for a week Source: Lung ILC2 Genotype: wildtype Strain: C57BL/6 Tissue: Lung Permissive Robust Mus musculus GSE111871 ... MA0002.2
RUNX1 TF-1 (erythroleukemia) Genotype: wildtype; Treatment: DOX for 6 days; Permissive Homo sapiens GSE73207 ... MA0002.2
RUNX1 TF-1 (erythroleukemia) Genotype: wildtype; Treatment: DOX for 6 days; Permissive Homo sapiens GSE73207 ... MA0002.2
RUNX1 TF-1 (erythroleukemia) Genotype: TF-1-RAD21 Q592*; Treatment: DOX for 6 days; Permissive Robust Homo sapiens GSE73207 ... MA0002.2
RUNX1 myeloid cell Sex: male; Tissue: Venous blood; Age: 45-50; Genotype: RUNX1 mutant; Permissive Homo sapiens GSE111821 ... MA0002.2
RUNX1 myeloid cell Sex: male; Tissue: Venous blood; Age: 45-50; Genotype: RUNX1 mutant; Permissive Homo sapiens GSE111821 ... MA0002.2
RUNX1 myeloid cell Sex: male; Tissue: Bone marrow; Age: 55-60; Genotype: RUNX1 mutant; Permissive Homo sapiens GSE111821 ... MA0002.2
RUNX1 myeloid cell Sex: male; Tissue: Venous blood; Age: 65-70; Genotype: RUNX1 mutant; Permissive Homo sapiens GSE111821 ... MA0002.2
RUNX1 cord blood CD34 cells Genotype: control; Permissive Homo sapiens GSE111917 ... MA0002.2
RUNX1 cord blood CD34 cells Genotype: RUNX1mut transduced; Permissive Robust Homo sapiens GSE111917 ... MA0002.2
RUNX1 iPSC (induced pluripotent stem cells) Characteristic: harvest time 31 day;Genotype: control; Permissive Homo sapiens GSE111917 ... MA0002.2
RUNX1 iPSC (induced pluripotent stem cells) Characteristic: harvest time 31 day; Treatment: dox; Genotype: DOX-induced RUNX1mut; Permissive Homo sapiens GSE111917 ... MA0002.2
RUNX1 iPSC (induced pluripotent stem cells) Characteristic: harvest time 34 day; Genotype: control; Permissive Homo sapiens GSE111917 ... MA0002.2
RUNX1 iPSC (induced pluripotent stem cells) Characteristic: harvest time 34 day; Treatment: dox; Genotype: DOX-induced RUNX1mut; Permissive Homo sapiens GSE111917 ... MA0002.2
RUNX1 ME-1 (acute myeloid leukemia ) Treatment: no dox; Genotype: CBFB-MYH11 knockdown construct, RUNX1 wildtype; Permissive Robust Homo sapiens GSE117138 ... MA0002.2
RUNX1 ME-1 (acute myeloid leukemia ) Treatment: 600 ng/ml doxycycline; Genotype: CBFB-MYH11 knockdown construct, RUNX1 knockdown; Permissive Robust Homo sapiens GSE117138 ... MA0002.2
RUNX1 fetal ovary Sex: Female; Developmental stage: E14.5; Strain: CD1; Permissive Robust Mus musculus GSE128767 ... MA0002.2
RUNX1 fetal ovary Sex: Female; Developmental stage: E14.5; Strain: CD1; Permissive Mus musculus GSE128767 ... MA0002.2
RUNX1 primary neurofibroma cells Genotype: Nf1fl/fl(knockout),DhhCre; Strain: C57BL/6-I129; Treatment: shRNA; Permissive Robust Mus musculus GSE122775 ... MA0002.2
RUNX1 VCaP (prostate carcinoma) DHT24H Permissive Homo sapiens GSE58428 MA0002.2
RUNX1 MARROW Permissive Robust Homo sapiens GSE64862 MA0002.2
RUNX1 K562 (myelogenous leukemia) Permissive Robust Homo sapiens ENCSR414TYY MA0002.2
RUNX1 K562 (myelogenous leukemia) Permissive Homo sapiens ENCSR588AKU MA0002.2
RUNX1 Jurkat E6.1 (T-cells) Permissive Robust Homo sapiens GSE17954 ... MA0002.2
RUNX1 embryonic stem cell-derived haematopoietic cells Permissive Robust Mus musculus GSE22178 ... MA0002.2
RUNX1 megakaryocytes Permissive Robust Homo sapiens GSE24674 ... MA0002.2
RUNX1 CMK (acute megakaryoblastic leukemia) Permissive Robust Homo sapiens GSE24777 ... MA0002.2
RUNX1 K562 (myelogenous leukemia) Permissive Robust Homo sapiens GSE24777 ... MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE29222 ... MA0002.2
RUNX1 Lin- SCA+ CD34+ hematopoietic stem cells Permissive Robust Mus musculus GSE31221 ... MA0002.2
RUNX1 L8057 (megakaryoblastic leukemia) Permissive Robust Mus musculus GSE33653 ... MA0002.2
RUNX1 thymocytes Permissive Robust Mus musculus GSE33653 ... MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE34540 ... MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE34540 ... MA0002.2
RUNX1 hematopoietic cells Permissive Robust Mus musculus GSE40235 ... MA0002.2
RUNX1 CD34+ hematopoietic stem cells Permissive Robust Homo sapiens GSE45144 ... MA0002.2
RUNX1 megakaryocytes Permissive Robust Mus musculus GSE45372 ... MA0002.2
RUNX1 BMiFLT3(15-3) (murine acute lymphoblastic leukemia) Permissive Robust Mus musculus GSE45377 ... MA0002.2
RUNX1 CD4+ CD25+ CD45RA+ T-cells Permissive Homo sapiens GSE43119 ... MA0002.2
RUNX1 CD4+ CD25- T-cells Permissive Robust Homo sapiens GSE43119 ... MA0002.2
RUNX1 CD4+ CD25- T-cells Permissive Robust Homo sapiens GSE43119 ... MA0002.2
RUNX1 mast cells Permissive Robust Mus musculus GSE48085 ... MA0002.2
RUNX1 mature megakaryocytes Permissive Mus musculus GSE42108 ... MA0002.2
RUNX1 myoblasts Permissive Robust Mus musculus GSE56077 ... MA0002.2
RUNX1 EML -C1(EML, clone 1) Permissive Robust Mus musculus GSE62596 ... MA0002.2
RUNX1 embryonic stem cell-derived myeloid progenitors Permissive Mus musculus GSE64589 ... MA0002.2
RUNX1 CD4+ T-cells Permissive Mus musculus GSE67443 ... MA0002.2
RUNX1 CD4+ T-cells Permissive Mus musculus GSE67443 ... MA0002.2
RUNX1 FDC-P1 (lymphoblasts) Permissive Robust Mus musculus GSE81179 ... MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE81321 ... MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Homo sapiens GSE76464 ... MA0002.2
RUNX1 MV-4-11 (Childhood acute monocytic leukemia) Permissive Robust Homo sapiens GSE79899 ... MA0002.2
RUNX1 THP-1 (acute monocytic leukemia) Permissive Robust Homo sapiens GSE79899 ... MA0002.2
RUNX1 NB4 (acute promyelocytic leukemia ) Permissive Robust Homo sapiens GSE81992 ... MA0002.2
RUNX1 Hoxb8-FL Permissive Robust Mus musculus GSE84328 ... MA0002.2
RUNX1 Jurkat (T-cells) Permissive Homo sapiens GSE85524 ... MA0002.2
RUNX1 HEK293T (embryonic kidney) Permissive Homo sapiens GSE85524 ... MA0002.2
RUNX1 peripheral blood mononuclear cells Permissive Robust Homo sapiens GSE85524 ... MA0002.2
RUNX1 SKH1 (chronic myelogenous leukemia, BCR-ABL1 positive) Permissive Robust Homo sapiens GSE87283 ... MA0002.2
RUNX1 SKH1 (chronic myelogenous leukemia, BCR-ABL1 positive) Permissive Robust Homo sapiens GSE87283 ... MA0002.2
RUNX1 embryonic fibroblasts Permissive Robust Mus musculus GSE90893 ... MA0002.2
RUNX1 embryonic fibroblasts expressing OSKM for 48h Permissive Mus musculus GSE90893 ... MA0002.2
RUNX1 natural killer T cells Permissive Robust Mus musculus GSE98662 ... MA0002.2
RUNX1 HL-60 (acute myeloid leukemia) Permissive Robust Homo sapiens GSE107553 ... MA0002.2
RUNX1 LPS141 (Dedifferentiated liposarcoma) Permissive Robust Homo sapiens GSE111253 ... MA0002.2
RUNX1 HL-60 (acute myeloid leukemia) Permissive Homo sapiens ERP008568 MA0002.2
RUNX1 SKNO-1 (acute myeloid leukemia) Permissive Homo sapiens GSE23730 MA0002.2
RUNX1 Jurkat (T-cells) Permissive Robust Homo sapiens GSE29180 MA0002.2
RUNX1 CCRF-CEM (T acute lymphoblastic leukemia) Permissive Robust Homo sapiens GSE33850 MA0002.2
RUNX1 Permissive Robust Homo sapiens GSE42075 MA0002.2
RUNX1 Jurkat (T-cells) Permissive Robust Homo sapiens GSE42575 MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE45738 MA0002.2
RUNX1 ME-1 (acute myeloid leukemia ) Permissive Robust Homo sapiens GSE46044 MA0002.2
RUNX1 Permissive Homo sapiens GSE60130 MA0002.2
RUNX1 TSU-1621-MT (adult acute myeloid leukemia) Permissive Robust Homo sapiens GSE60477 MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE62847 MA0002.2
RUNX1 CD34+ cells Permissive Robust Homo sapiens GSE64862 MA0002.2
RUNX1 Permissive Robust Homo sapiens GSE65313 MA0002.2
RUNX1 Kasumi-1 (acute myeloblastic leukemia) Permissive Robust Homo sapiens GSE65427 MA0002.2
RUNX1 U937 (adult acute monocytic leukemia) Permissive Robust Homo sapiens GSE65427 MA0002.2
RUNX1 Jurkat (T-cells) Permissive Robust Homo sapiens GSE68976 MA0002.2
RUNX1 MCF7 (Invasive ductal breast carcinoma) Permissive Robust Homo sapiens GSE75070 MA0002.2
RUNX1 Jurkat (T-cells) Permissive Robust Homo sapiens GSE76181 MA0002.2
RUNX1 CD34+ cells ADULT Permissive Robust Homo sapiens GSE70660 MA0002.2
RUNX1 CD34+ cells FETAL Permissive Robust Homo sapiens GSE70660 MA0002.2