Detailed information of STAT3

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Dataset summary

TF Name: STAT3 Species: Homo sapiens
Cell-type/Tissue: MCF10A (breast epithelial cells) Condition/Source: 12 hours with 1 uM 4-hydroxytamoxifen dissolved in ethanol (Struhl)
JASPAR ID: MA0144.2 Collections: Permissive Robust
References: ENCODE ENCSR000DOQ GTRD EXP010547

External links

Models for profile: MA0144.2

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Summary plots

Statistical details

Model Peak caller Model ID Enrichment Zone TFBSs Score threshold Centrality p-value (log10)
DAMO MACS MA0144.2 69 38533 83.6 -15.7756883555579

112 datasets found for the same TF (STAT3) in other cell-types/tissues

TF Name Cell-line Condition/Source Collections Species Identifiers JASPAR ID
STAT3 MCF10A (breast epithelial cells) (To replace TAM_1uM_36hr) 36 h with 1 uM 4-hydroxytamoxifen (Myers) Permissive Robust Homo sapiens ENCSR000DPB MA0144.2
STAT3 CD4+ T-cells IL-6, IL-23 Permissive Robust Mus musculus GSE23681 ... MA0144.2
STAT3 dendritic cells IL21 Permissive Robust Mus musculus GSE27161 ... MA0144.2
STAT3 dendritic cells IL-21 and GM-CSF Permissive Robust Mus musculus GSE27161 ... MA0144.2
STAT3 adherent peritoneal exudate macrophages Il10 Permissive Mus musculus GSE31529 ... MA0144.2
STAT3 dendritic cells LPS, 0 min Permissive Mus musculus GSE36099 ... MA0144.2
STAT3 dendritic cells LPS, 120 min Permissive Mus musculus GSE36099 ... MA0144.2
STAT3 dendritic cells LPS, 60 min Permissive Mus musculus GSE36099 ... MA0144.2
STAT3 AtT-20 (pituitary tumor) LIF Permissive Robust Mus musculus GSE37235 ... MA0144.2
STAT3 AtT-20 (pituitary tumor) Dex+LIF Permissive Robust Mus musculus GSE37235 ... MA0144.2
STAT3 CD4+ T-cells IL21 Permissive Robust Mus musculus GSE39756 ... MA0144.2
STAT3 gastric tumors PBS Permissive Mus musculus GSE48285 ... MA0144.2
STAT3 gastric tumors IL6 Permissive Mus musculus GSE48285 ... MA0144.2
STAT3 gastric tumors IL11 Permissive Mus musculus GSE48285 ... MA0144.2
STAT3 CD4+ T-cells IL21 Permissive Mus musculus GSE63204 ... MA0144.2
STAT3 CD4+ T-cells Stat1 KO, IL21 Permissive Mus musculus GSE63204 ... MA0144.2
STAT3 CD4+ T-cells 3 day in vitro culture for Th0, treatment (IL6) Permissive Robust Mus musculus GSE65621 ... MA0144.2
STAT3 CD4+ T-cells 3 day in vitro culture for Th0, treatment (IL27) Permissive Robust Mus musculus GSE65621 ... MA0144.2
STAT3 CD4+ T-cells 3 day in vitro culture for Th0, STAT1 KO Permissive Mus musculus GSE65621 ... MA0144.2
STAT3 CD4+ T-cells 3 day in vitro culture for Th0, treatment (IL6), STAT1 KO Permissive Robust Mus musculus GSE65621 ... MA0144.2
STAT3 CD4+ T-cells 3 day in vitro culture for Th0, treatment (IL27), STAT1 KO Permissive Robust Mus musculus GSE65621 ... MA0144.2
STAT3 dendritic cells SAHA (500nm) Permissive Mus musculus GSE74262 ... MA0144.2
STAT3 mammary gland lactation day one Permissive Mus musculus GSE84115 ... MA0144.2
STAT3 mammary gland involution 12 hours Permissive Robust Mus musculus GSE84115 ... MA0144.2
STAT3 mammary gland involution 24 hours Permissive Robust Mus musculus GSE84115 ... MA0144.2
STAT3 MDA-MB-157 (triple negative breast carcinoma) ethanol Permissive Robust Homo sapiens GSE85579 ... MA0144.2
STAT3 MDA-MB-231 (breast adenocarcinoma) ethanol Permissive Robust Homo sapiens GSE85579 ... MA0144.2
STAT3 HCC1143 (ductal breast carcinoma) ethanol Permissive Homo sapiens GSE85579 ... MA0144.2
STAT3 HCC70 (ductal breast carcinoma) ethanol Permissive Robust Homo sapiens GSE85579 ... MA0144.2
STAT3 MDA-MB-468 (breast adenocarcinoma) ethanol Permissive Robust Homo sapiens GSE85579 ... MA0144.2
STAT3 bone marrow-derived macrophages 30min IL-10 Permissive Robust Mus musculus GSE86169 ... MA0144.2
STAT3 bone marrow-derived macrophages 195min LPS Permissive Mus musculus GSE86169 ... MA0144.2
STAT3 bone marrow-derived macrophages 195min LPS + 30min IL-10 Permissive Robust Mus musculus GSE86169 ... MA0144.2
STAT3 primary cortical oligodendrocyte progenitors 100ng/ml of CNTF (Peprotech) for 15 m Permissive Robust Mus musculus GSE99708 ... MA0144.2
STAT3 CD4+ T-cells IRF4 KO; pre IL21 Permissive Mus musculus GSE19198 ... MA0144.2
STAT3 CD4+ T-cells IRF4 KO; post IL21 Permissive Mus musculus GSE19198 ... MA0144.2
STAT3 Th17-cells 16h Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells 3h Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells STAT3 ko Permissive Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells RORg wt Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells RORg ko Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells RORg wt Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells RORg ko Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 spleen T cells CD4 Permissive Mus musculus GSE102317 ... MA0144.2
STAT3 spleen T cells IL-21 (100 ng/ml) for 1h, CD4 Permissive Robust Mus musculus GSE102317 ... MA0144.2
STAT3 TMD8 (diffuse large B-cell lymphoma) DMSO Permissive Homo sapiens GSE106844 ... MA0144.2
STAT3 TMD8 (diffuse large B-cell lymphoma) AZD1480(JAK inhibitor) for 4hrs Permissive Homo sapiens GSE106844 ... MA0144.2
STAT3 OCI-LY10 (diffuse large B-cell lymphoma) DMSO Permissive Homo sapiens GSE106844 ... MA0144.2
STAT3 OCI-LY10 (diffuse large B-cell lymphoma) AZD1480(JAK inhibitor) for 4hrs Permissive Homo sapiens GSE106844 ... MA0144.2
STAT3 MCF10A-ER-Src Genotype: non-transformed Permissive Robust Homo sapiens GSE115597 ... MA0144.2
STAT3 MCF10A-ER-Src Genotype: transformed Permissive Robust Homo sapiens GSE115597 ... MA0144.2
STAT3 EML -C1(EML, clone 1) Strain: B6D2F1 Genotype: CD34 positive Permissive Mus musculus GSE100689 ... MA0144.2
STAT3 kidney WT; lactation day 10 Permissive Mus musculus GSE115368 ... MA0144.2
STAT3 kidney Wap-E12-Ramp3; lactation day 10 Permissive Mus musculus GSE115368 ... MA0144.2
STAT3 AtT-20 (pituitary tumor) Treatment: 30 minutes LIF and Dexamethasone Cell type: pituitary corticotroph cell Passage: 10-20 Genotype: expressing 3x flag-Neo Permissive Robust Mus musculus GSE87180 ... MA0144.2
STAT3 AtT-20 (pituitary tumor) Treatment: 30 minutes LIF and Dexamethasone Cell type: pituitary corticotroph cell Passage: 10-20 Genotype: expressing 3x flag-Pax7 Permissive Robust Mus musculus GSE87180 ... MA0144.2
STAT3 AtT-20 (pituitary tumor) Treatment: 30 minutes of LIF and Dexamethasone, >20 days of 4-hydroxy-tamoxifen Cell type: Genotype:3x flag-ER-Pax8 Cell type: pituitary corticotroph cell Passage: 10-20 Permissive Robust Mus musculus GSE87180 ... MA0144.2
STAT3 AtT-20 (pituitary tumor) Treatment: 30 minutes of LIF and Dexamethasone, >20 days of 4-hydroxy-tamoxifen followed by 18 days of Ethanol treatment Cell type: Genotype:3x flag-ER-Pax9 Cell type: pituitary corticotroph cell Passage: 10-20 Permissive Robust Mus musculus GSE87180 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: DN-NFkB for 2 hr Permissive Mus musculus GSE96767 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: IL-1b (10ng/ml) + DN-NFkB for 2 hr Permissive Mus musculus GSE96767 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: IL-6 (10ng/ml) + DN-NFkB for 2 hr Permissive Robust Mus musculus GSE96767 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: IL-1b (10ng/ml) and IL-6 (10ng/ml) + DN-NFkB for 2 hr Permissive Robust Mus musculus GSE96767 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: IL-1b (10ng/ml) for 2 hr Permissive Robust Mus musculus GSE96767 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: IL-6 (10ng/ml) for 2 hr Permissive Robust Mus musculus GSE96767 ... MA0144.2
STAT3 primary hepatocytes Strain: C57BL/6 Source: primary mouse hepatocytes Treatment: IL-1b (10ng/ml) and IL-6 (10ng/ml) for 2 hr Permissive Robust Mus musculus GSE96767 ... MA0144.2
STAT3 JB6 (Human anaplastic large cell lymphoma) Treatment: DMSO for 3 hrs Permissive Robust Homo sapiens GSE117164 ... MA0144.2
STAT3 JB6 (Human anaplastic large cell lymphoma) Treatment: 300 nM Crizotinib for 3 hrs Permissive Robust Homo sapiens GSE117164 ... MA0144.2
STAT3 SU-DHL-1 (Anaplastic large cell lymphoma) Treatment: DMSO for 3 hrs Permissive Robust Homo sapiens GSE117164 ... MA0144.2
STAT3 SU-DHL-1 (Anaplastic large cell lymphoma) Treatment: 300 nM Crizotinib for 3 hrs Permissive Robust Homo sapiens GSE117164 ... MA0144.2
STAT3 cultured GC B cells Genotype: STAT3 wildtype Strain: C57BL/6 Permissive Mus musculus GSE120022 ... MA0144.2
STAT3 gastric tumors Treatment: PBS; Age: 10-12 weeks; Genotype: gp130F/F; Permissive Mus musculus GSE48287 ... MA0144.2
STAT3 gastric tumors Treatment: IL6; Age: 10-12 weeks; Genotype: gp130F/F; Permissive Robust Mus musculus GSE48287 ... MA0144.2
STAT3 gastric tumors Treatment: IL11; Age: 10-12 weeks; Genotype: gp130F/F; Permissive Robust Mus musculus GSE48287 ... MA0144.2
STAT3 inducible motor neuron embryonic stem cells Treatment: without Doxycycline treatment; Permissive Mus musculus GSE50993 ... MA0144.2
STAT3 inducible motor neuron embryonic stem cells Treatment: without Doxycycline treatment; Permissive Mus musculus GSE50993 ... MA0144.2
STAT3 inducible motor neuron embryonic stem cells Treatment: Doxycycline treatment; Permissive Mus musculus GSE50993 ... MA0144.2
STAT3 pre-activated CD4+ T cells Treatment: none (untreated); Tissue: Spleen; Strain: C57BL/6; Permissive Mus musculus GSE61677 ... MA0144.2
STAT3 pre-activated CD4+ T cells Treatment: IL-21 for 1hr; Tissue: Spleen; Strain: C57BL/6; Permissive Mus musculus GSE61677 ... MA0144.2
STAT3 splenic conventional dendritic cells Treatment: none (untreated); Tissue: Spleen; Strain: C57BL/6; Permissive Mus musculus GSE61677 ... MA0144.2
STAT3 splenic conventional dendritic cells Treatment: IL-21 for 1hr; Tissue: Spleen; Strain: C57BL/6; Permissive Mus musculus GSE61677 ... MA0144.2
STAT3 HeLa S3 (cervical adenocarcinoma) Permissive Robust Homo sapiens ENCSR000EDC MA0144.2
STAT3 Th17-cells Permissive Robust Mus musculus GSE26552 ... MA0144.2
STAT3 Th17-cells Permissive Mus musculus GSE21669 ... MA0144.2
STAT3 embryonic stem cells Permissive Robust Mus musculus GSE11431 ... MA0144.2
STAT3 dendritic cells Permissive Mus musculus GSE27161 ... MA0144.2
STAT3 adherent peritoneal exudate macrophages Permissive Mus musculus GSE31529 ... MA0144.2
STAT3 CD4+ T-cells Permissive Mus musculus GSE39756 ... MA0144.2
STAT3 Th17-cells Permissive Mus musculus GSE39756 ... MA0144.2
STAT3 astrocytes Permissive Robust Mus musculus GSE51281 ... MA0144.2
STAT3 dendritic cells Permissive Mus musculus GSE74262 ... MA0144.2
STAT3 HUES64 (embryonic stem cells) Permissive Homo sapiens GSE61475 ... MA0144.2
STAT3 HUES64 (embryonic stem cells) Permissive Homo sapiens GSE61475 ... MA0144.2
STAT3 HUES64 (embryonic stem cells) Permissive Homo sapiens GSE61475 ... MA0144.2
STAT3 Th17-cells Permissive Robust Homo sapiens GSE67183 ... MA0144.2
STAT3 A139 ER-, PR-, HER2- breast cancer cells N/A Permissive Homo sapiens GSE85579 ... MA0144.2
STAT3 A137 ER-, PR-, HER2- breast cancer cells N/A Permissive Homo sapiens GSE85579 ... MA0144.2
STAT3 bone marrow-derived macrophages Permissive Mus musculus GSE86169 ... MA0144.2
STAT3 CD4+ T-cells Permissive Mus musculus GSE19198 ... MA0144.2
STAT3 CD4+ T-cells Permissive Robust Mus musculus GSE19198 ... MA0144.2
STAT3 Th0-cells Permissive Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 Th17-cells Permissive Robust Mus musculus GSE40918 ... MA0144.2
STAT3 NCI-H358 (human nnon small cell lung cancer cell line) Permissive Robust Homo sapiens GSE79707 ... MA0144.2
STAT3 AGS (gastric adenocarcinoma) Permissive Robust Homo sapiens GSE79707 ... MA0144.2
STAT3 WA01 (H1, human embryonic stem cells) Permissive Homo sapiens ERP004237 MA0144.2
STAT3 OCI-LY10 (diffuse large B-cell lymphoma) Permissive Homo sapiens GSE50723 MA0144.2
STAT3 OCI-LY19 (diffuse large B-cell lymphoma) Permissive Homo sapiens GSE50723 MA0144.2
STAT3 OCI-LY3 (diffuse large B-cell lymphoma) Permissive Robust Homo sapiens GSE50723 MA0144.2
STAT3 SU-DHL-2 (anaplastic large cell lymphoma) Permissive Homo sapiens GSE50723 MA0144.2
STAT3 SU-DHL-6 (diffuse large B-cell lymphoma) Permissive Homo sapiens GSE50723 MA0144.2
STAT3 U2932 (diffuse large B-cell lymphoma) Permissive Robust Homo sapiens GSE50723 MA0144.2
STAT3 hFOB 1.19 (fetal osteoblast) Permissive Homo sapiens GSE82295 MA0144.2